NFL picks, predictions, odds for Week 10

NFL Picks, Predictions, and Odds for Week 10

As NFL Week 10 arrives, it's time to review the odds and make predictions for the upcoming weekend of the 2025 regular season. With the trade deadline behind us and the season past its halfway mark, playoff and division races are taking shape.

Key Matchup: Denver Broncos vs. Las Vegas Raiders

Thursday night's AFC West game between the Denver Broncos and Las Vegas Raiders will play an important role in the playoff battles.

Recap of Week 9

Favorites dominated Week 9 with a 10-2 record. However, Week 10 brought numerous upsets and surprises:

Teams Returning and Resting in Week 10

This week, four teams return from a bye: the Cleveland Browns, New York Jets, Philadelphia Eagles, and Tampa Bay Buccaneers. Meanwhile, the Cincinnati Bengals, Dallas Cowboys, Kansas City Chiefs, and Tennessee Titans have a brief pause.

Schedule Highlights

"After the favorites cruised to a 10-2 record in Week 9, Week 10 was a rough week of upsets and bad beats."

Author's summary: The NFL's Week 10 shifts momentum with surprising results and key teams returning, intensifying the playoff race as the season progresses.

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ClutchPoints ClutchPoints — 2025-11-07