Tulyp Medical, a spin-off from Sofinnova Partners' medtech accelerator Sofinnova MD Start, is developing a medical device system designed to oxygenate tissue that might otherwise be obstructed, potentially preventing complications such as amputations or death.
While many perfusion systems concentrate on monitoring blood flow during oxygen delivery, Tulyp's technology emphasizes controlling blood pressure. The system targets a vascular blood pressure benchmark of 120/80 mmHg, which is widely recognized as the normal standard.
By leveraging blood pressure, a biological factor often overlooked in favor of flow, Tulyp aims to optimize oxygen delivery and minimize variability in vascular procedures. This approach acknowledges the body's natural response to pressure rather than using fixed flow rates.
“Between two individuals of vastly different heights, there’s a difference in what they need if you were to provide flow, but if you provide patients with perfusion based off of 120/80mmHg, a pressure the body readily understands, then their bodies can demand what they need.”
— Mano Iyer, CEO of Tulyp Medical
Mano Iyer also emphasized the dynamic nature of blood pressure: “Pressure is in a constant state of flux in all of us at any given point in time.” This variability reinforces the importance of personalized perfusion strategies.
Tulyp Medical’s pressure-based perfusion system offers a promising innovation in vascular care by adapting oxygen delivery to individual physiological needs, potentially improving outcomes in critical tissue oxygenation.
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