UTSA vs. South Florida odds, line: 2025 college football picks for Week 11 predictions from proven model

UTSA vs. South Florida Odds and Predictions for Week 11

The South Florida Bulls aim to remain competitive in the American Athletic Conference championship race as they face the UTSA Roadrunners in a critical Thursday night game. UTSA recently triumphed 48-26 over Tulane on October 30, while South Florida seeks to bounce back from a 31-24 defeat at Memphis.

Team Records and Standings

UTSA Roadrunners: 4-4 overall, 2-2 in AAC, ranked eighth in the league
South Florida Bulls: 6-2 overall, 3-1 in AAC, tied for fourth place
UTSA’s road record this season is 1-3
South Florida is undefeated at home with a 4-0 record

Scoring Trends

The Over has hit in the last three UTSA games
The Over is 5-1 in South Florida's last six games

Game Details

The game kicks off at 7:30 p.m. at Raymond James Stadium in Tampa, Florida. In their only previous encounter, UTSA defeated South Florida 49-21 in 2023.

Betting Odds

South Florida is favored by 14 points
Over/Under for total points scored is set at 67.5
Money line odds: South Florida -610 (risk $610 to win $100), UTSA +445 (risk $100 to win $445)

The SportsLine Projection Model “simulates every FBS game 10,000 times” to provide college football predictions and betting advice.

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Author’s summary: This matchup between South Florida and UTSA is pivotal for AAC standings, featuring strong home-field advantage for the Bulls and high-scoring trends on both sides.

SportsLine — 2025-11-06

UTSA vs. South Florida Odds and Predictions for Week 11

Team Records and Standings

Scoring Trends

Game Details

Betting Odds

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