Heart Health: Long-Term Melatonin Use Linked to Cardiovascular Risk
New research indicates that people with insomnia who take melatonin supplements for over a year may face a higher risk of heart failure compared to those who do not use this sleep aid. The study found that long-term melatonin use is associated with an increased likelihood of heart failure diagnosis, hospitalization, or death from any cause.
This research was presented at the American Heart Association’s Scientific Sessions 2025 in New Orleans. However, the findings are preliminary and have not yet undergone peer review in a scientific journal.
Study Limitations and Safety Concerns
The researchers emphasize that their study does not prove a direct cause-and-effect link between melatonin use and heart failure. Still, the results raise important safety questions about prolonged melatonin use and suggest the need for further investigation into the cardiovascular effects of these supplements.
Regulation and Usage Issues
- Melatonin supplements are widely available over-the-counter without prescriptions.
- These products are largely unregulated and often used without medical supervision.
- Researchers caution that melatonin "may not be as harmless as commonly assumed."
“Melatonin supplements may not be as harmless as commonly assumed.”
Because of the potential risks, medical professionals should carefully consider advising patients on melatonin use, especially for long-term treatment.
Author's Summary
Long-term melatonin use in people with insomnia may raise heart failure risks, highlighting the need for careful evaluation and further cardiovascular safety research.
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